Italian Prime Minister Berlusconi recently called himself the most persecuted person “in the entire history of the world”.  Berlusconi 'most persecuted man' That gets me thinking - who has been the most persecuted ever?  I think the easy answer is Jesus Christ.  But who is next?  I think we'll confine this to major figures over the course of time.  George W. Bush is one.  Perhaps the Rosenbergs?  I don't know...it's a hard question to answer.